ECV may be expanded in children with cancer but the recorded difference in ECV/BSA is probably related to differences in patient size and a nonproportionate relationship between ECV and BSA.
In children from centre 1, ECV/BSA, but not ECV/eECV, was significantly higher in cancer patients.ĮCV is expanded in female cancer patients but not male cancer patients. In women from both centres, however, they were both significantly higher in cancer patients than in noncancer patients and, in centre 2, than in donors. The serum sodium concentration is a measure of water status rather than total body salt content. In men from both centres, neither ECV/BSA nor ECV/lean body mass showed an increase in cancer patients. Sodium is a major osmotic solute in the extracellular fluid and is therefore an important determinant of the extracellular volume status, serum osmolality, and tonicity. Gender : Weight : Intracellular fluid (ICF): inside cells. Volume depletion, or extracellular fluid (ECF) volume contraction, occurs as a result of loss of total body sodium. This calculator provides estimates of these fluid volumes based on a few variables. The major division is into Intracellular Fluid (ICF: about 23 liters) and Extracellular Fluid (ECF: about. ECV was also expressed in adults in relation to lean body mass and in children as a fraction of ECV estimated from height and weight (eECV). The two main fluid compartments are the intracellular (space within the organism's cells) and extracellular compartments (separated by semi-permeable membranes). These collections are referred to as compartments. ECV/BSA was calculated as the quotient, GFR/BSA:GFR/ECV. GFR/ECV was measured from the exponential rate constant with an appropriate one-compartment correction. GFR was measured with Cr-EDTA and the slope-intercept technique in patients from two hospitals, the first using three samples (540 adults, including 382 with cancer, and 124 children, including 40 with cancer) and the second using four samples (256 adults, including 132 with cancer and 75 donors), scaled to body surface area (BSA) of 1.73 m and corrected using Brochner-Mortensen's equations (GFR/BSA). The aim was to test this concern by measuring ECV in cancer patients in comparison with noncancer patients and healthy kidney donors. Ohashi Y, Mizuiri S, Aikawa A, Sakai K, et al. Cancer patients may have extracellular fluid volume (ECV) abnormalities that potentially invalidate glomerular filtration rate (GFR) measured using the slope-intercept technique. Among the MIA and fluid volume components, serum albumin, SGA score, and nPCR were significantly.
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